BDBM7238 (3Z)-3-(1H-imidazol-5-ylmethylidene)-5-methoxy-2,3-dihydro-1H-indol-2-one::3-(3H-Imidazol-4-ylmethylene)-5-methoxy-1,3-dihydro-indol-2-one::SU9516::cid_5289419::imidazole indolinone driv.

SMILES COc1ccc2NC(=O)C(=Cc3cnc[nH]3)c2c1

InChI Key InChIKey=QNUKRWAIZMBVCU-UHFFFAOYSA-N

Data  16 IC50  3 EC50

PDB links: 5 PDB IDs match this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 7238   

TargetCyclin-dependent kinase 5(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL

LigandBDBM7238((3Z)-3-(1H-imidazol-5-ylmethylidene)-5-methoxy-2,3...)Copy SMILESCopy InChI

Affinity DataIC50:  65nMAssay Description:Inhibition of CDK5More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseMMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
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